https://doi.org/10.4081/reumatismo.2013.4
Italian Society of Rheumatology recommendations for the management of gout
Submitted: 24 February 2013
Accepted: 27 February 2013
Published: 28 March 2013
Accepted: 27 February 2013
Abstract Views: 5491
PDF: 1475
Publisher's note
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Methods: The multidisciplinary group of experts included rheumatologists, general practitioners, internists, geriatricians, nephrologists, cardiologists and evidence-based medicine experts. To maintain consistency with EULAR recommendations, a similar methodology was utilized by the Italian group. The original propositions were translated in Italian and priority research queries were identified through a Delphi consensus approach. A systematic search was conducted for selected queries. Efficacy and safety data on drugs reported in RCTs were combined in a meta-analysis where feasible. The strength of recommendation was measured by utilising the EULAR ordinal and visual analogue scales.
Results: The original 12 propositions were translated and adapted to Italian context. Further evidences were collected about the role of diet in the non-pharmacological treatment of gout and the efficacy of oral corticosteroids and low-dose colchicine in the management of acute attacks. Statements concerning uricosuric treatments were withdrawn and replaced with a proposition focused on a new urate lowering agent, febuxostat. A research agenda was developed to identify topics still not adequately investigated concerning the management of gout.
Conclusions: The SIR has developed updated recommendations for the management of gout adapted to the Italian healthcare system. Their implementation in clinical practice is expected to improve the management of patients with gout.
How to Cite
Manara, M., Bortoluzzi, A., Favero, M., Prevete, I., Scirè, C., Bianchi, G., … Minisola, G. (2013). Italian Society of Rheumatology recommendations for the management of gout. Reumatismo, 65(1), 4–21. https://doi.org/10.4081/reumatismo.2013.4
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