https://doi.org/10.4081/reumatismo.2013.207

Systematic review of 2008-2012 literature and update of recommendations for the use of methotrexate in rheumatic diseases, with a focus on rheumatoid arthritis

Vol. 65 No. 5 (2013)
Submitted: 2 September 2013
Accepted: 6 November 2013
Published: 18 December 2013
Recommendations, Evidence-based medicine, Methotrexate, Rheumatoid arthritis, Rheumatic diseases.
Abstract Views: 4093
PDF: 2530
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

M. Todoerti
Rheumatology, IRCCS S. Matteo, University of Pavia, Italy.
W. Maglione
Rheumatology, Istituto Ortopedico G. Pini, Milan, Italy.
E. Bernero
Rheumatology, University of Genoa, Italy.
A. Bortoluzzi
Rheumatology, University of Ferrara, Italy.
M. Colaci
michelecolaci@virgilio.it
Rheumatology, University of Modena and Reggio Emilia, Italy.
E. Galuppi
Rheumatology, University of Ferrara, Italy.
S. Paolino
Rheumatology, University of Genoa, Italy.
R. Talarico
Rheumatology, University of Pisa, Italy.
M. Cutolo
Reumatologia, Università di Genova, Italy.
C. Ferri
Rheumatology, University of Modena and Reggio Emilia, Italy.
F. Trotta
Rheumatology, University of Ferrara, Italy.
S. Bombardieri
Rheumatology, University of Pisa, Italy.
C.M. Montecucco
Rheumatology, IRCCS S. Matteo, University of Pavia, Italy.
L. Sinigaglia
Rheumatology, Istituto Ortopedico G. Pini, Milan, Italy.
The objective of this review is to update the recommendations of the 2010 Italian Consensus on the use of methotrexate (MTX) in rheumatoid arthritis (RA) and other rheumatic diseases. The literature published between 2008 and 2012 was systematically reviewed and updated recommendations on MTX use in rheumatic diseases, particularly RA, were formulated. These recommendations were approved by a panel of expert Italian Rheumatologists. A total of 10,238 references were identified, among which 70 studies were selected for critical evaluation. Sufficient evidence had accumulated to warrant changes to several of the recommendations in the new version. A new recommendation for patients with RA who are in MTX-induced clinical remission was also proposed and approved by the panel. Updated recommendations for the use of MTX in patients with RA or other rheumatologic disease are proposed.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC

How to Cite

Todoerti, M., Maglione, W., Bernero, E., Bortoluzzi, A., Colaci, M., Galuppi, E., … Sinigaglia, L. (2013). Systematic review of 2008-2012 literature and update of recommendations for the use of methotrexate in rheumatic diseases, with a focus on rheumatoid arthritis. Reumatismo, 65(5), 207–218. https://doi.org/10.4081/reumatismo.2013.207

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Similar Articles

<< < 27 28 29 30 31 32 33 34 35 36 > >> 

You may also start an advanced similarity search for this article.