A case of propylthiouracil-induced antineutrophilic cytoplasmic antibody-positive vasculitis successfully treated with radioactive iodine

Submitted: 3 August 2012
Accepted: 11 June 2013
Published: 24 July 2013
Abstract Views: 2614
PDF: 624
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Antineutrophilic cytoplasmic antibody (ANCA) associated vasculitis is one of the rare complications of propylthiouracil treatment. Having a variable clinical spectrum, it may be presented with both skin limited vasculitis and life-threatening systemic vasculitis. In this study, we present a case that developed ANCA-positive vasculitis with skin and kidney involvement (hematuria and proteinuria) six months after propylthiouracil treatment was initiated for toxic nodular goiter. Proteinuria recovered dramatically subsequent to radioactive iodine treatment following ceasing the drug.

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Bes, C., Dikbaş, O., Keskin, E., Kaptanoğulları, Ö., & Soy, M. (2013). A case of propylthiouracil-induced antineutrophilic cytoplasmic antibody-positive vasculitis successfully treated with radioactive iodine. Reumatismo, 65(3), 131–133. https://doi.org/10.4081/reumatismo.2013.131

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