https://doi.org/10.4081/reumatismo.2012.88

Biomarkers and prognostic stratification in psoriatic arthritis

Vol. 64 No. 2 (2012)
Submitted: 30 April 2012
Accepted: 5 June 2012
Published: 5 June 2012
psoriatic arthritis, biomarkers, joint damage
Abstract Views: 1298
PDF: 1267
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

L. Bogliolo
IRCCS Fondazione Policlinico S. Matteo, Italy.
G. Crepaldi
IRCCS Fondazione Policlinico S. Matteo, Italy.
R. Caporali
caporali@smatteo.pv.it
IRCCS Fondazione Policlinico S. Matteo, Italy.
In rheumatic diseases, biomarkers may serve as surrogate endpoints for diagnosis, prognosis, disease activity, therapeutic response and disease outcome. In recent years a great effort has been made to identify useful tools to establish early diagnosis, prognosis and therapeutic response especially in rheumatoid arthritis (RA). In psoriatic arthritis (PsA) serological biomarkers have been frequently borrowed from RA, but this approach have sometimes lead to inappropriate choices of biomarkers and incorrect conclusions. Furthermore, the heterogeneous spectrum of articular manifestation of PsA and the variable course of the disease can make diagnosis and prognosis difficult. Recently, the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) identified two key areas for biomarkers development in psoriasis and PsA: the diagnosis of the articular disease in patients with psoriasis and the evaluation of joint damage in PsA. In this review we revised the currently available and the new potential markers for PsA, such as serum, genetic, cellular and histological biomarkers, clinical and imaging data, with particular attention on the prognostic aspect in order to identify progressive disease suitable for a more aggressive treatment.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
L. Bogliolo, IRCCS Fondazione Policlinico S. Matteo

UOC Reumatologia

G. Crepaldi, IRCCS Fondazione Policlinico S. Matteo

UOC Reumatologia

R. Caporali, IRCCS Fondazione Policlinico S. Matteo

UOC Reumatologia

How to Cite

Bogliolo, L., Crepaldi, G., & Caporali, R. (2012). Biomarkers and prognostic stratification in psoriatic arthritis. Reumatismo, 64(2), 88–98. https://doi.org/10.4081/reumatismo.2012.88

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Similar Articles

<< < 34 35 36 37 38 39 40 41 42 43 > >> 

You may also start an advanced similarity search for this article.