https://doi.org/10.4081/reumatismo.2012.40

IgA deficiency evidence after anti-TNF-α treatment in a psoriatic arthritis patient: case report

Vol. 64 No. 1 (2012)
Submitted: 27 October 2011
Accepted: 26 January 2012
Published: 19 March 2012
IgA deficiency, TNF-α blocking therapy, psoriatic arthritis, infective diseases
Abstract Views: 819
PDF: 1477
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

S. Iervolino
University of Naples Federico II, Italy.
M. Lofrano
University of Naples Federico II, Italy.
M.N.D. Di Minno
University of Naples Federico II, Italy.
F. Foglia
University Federico II of Naples, Italy.
R. Scarpa
University of Naples Federico II, Italy.
R. Peluso
rosario.peluso2@unina.it
University of Naples Federico II, Italy.
It is known that the use of anti-TNF-α drugs is related to an increased incidence of infective diseases. This therapy can not be administered to patients having active infections and it has to be considered with caution in case of acquired or congenital immunodeficiency diseases. We report the case of a 28-years-old man affected by psoriatic arthritis; he developed some infections during treatment with TNF-α blockers. The infections were caused by a selective IgA deficiency, that was not evident before the anti-TNF-α blockers administration and disappeared after withdrawing the biological therapy. This case-report draws our attention to the possibility of cases of subclinical immunodeficiency, unknown by the patients, but important in the prognosis and in the therapeutic approach to these diseases. Therefore, it is important to evaluate carefully the immunologic status of patients during the pre-therapeutic screening for TNF-α blocking therapy.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
S. Iervolino, University of Naples Federico II
Department of Clinical and Experimental Medicine
M. Lofrano, University of Naples Federico II
Department of Clinical and Experimental Medicine
M.N.D. Di Minno, University of Naples Federico II
Department of Clinical and Experimental Medicine
F. Foglia, University Federico II of Naples
Department of Clinical and Experimental Medicine
R. Scarpa, University of Naples Federico II
Department of Clinical and Experimental Medicine
R. Peluso, University of Naples Federico II
Departmento of Clincal and Experimental Medicine

How to Cite

Iervolino, S., Lofrano, M., Di Minno, M., Foglia, F., Scarpa, R., & Peluso, R. (2012). IgA deficiency evidence after anti-TNF-α treatment in a psoriatic arthritis patient: case report. Reumatismo, 64(1), 40–43. https://doi.org/10.4081/reumatismo.2012.40

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Similar Articles

<< < 14 15 16 17 18 19 20 21 22 23 > >> 

You may also start an advanced similarity search for this article.