https://doi.org/10.4081/reumatismo.2011.63

‘ASIA’ - Autoimmune/inflammatory syndrome induced by adjuvants: even and odd

Vol. 63 No. 2 (2011)
Autoimmunity, adjuvant, vaccine, silicone.
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Authors

C. Perricone
carlo.perricone@gmail.com
Reumatologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Italy.
C. Alessandri
Reumatologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Italy.
G. Valesini
Reumatologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Italy.
Recently, Shoenfeld and Agmon-Levin described a potential new syndrome, namely ASIA - autoimmune/inflammatory syndrome induced by adjuvants, that comprises four medical conditions: siliconosis, the Gulf war syndrome, the macrophagic myofasciitis syndrome and post-vaccination phenomena, characterized by hyperactive immune responses accompanied by a similar complex of signs and symptoms. Most relevantly, these conditions share a linkage represented by adjuvants. This common soil may possibly induce autoimmune or auto-inflammatory diseases in humans as it was demonstrated in different animal models. Reconsidering under a unified umbrella this apparently detached condition is not only intriguing, but also provocative, and may help in unraveling novel pathogenetic mechanisms, preventive measures, and therapeutic targets.

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How to Cite

Perricone, C., Alessandri, C., & Valesini, G. (2011). ‘ASIA’ - Autoimmune/inflammatory syndrome induced by adjuvants: even and odd. Reumatismo, 63(2), 63–66. https://doi.org/10.4081/reumatismo.2011.63

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