https://doi.org/10.4081/reumatismo.2011.253

Cardiovascular and renal effects of hyperuricaemia and gout

Vol. 63 No. 4 (2011): Special issue • Microcrystalline Arthritis
hyperuricaemia, gout, cv risk, kidney, organ damage.
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Authors

F. Viazzi
francesca.viazzi@unige.it
University of Genoa, Italy.
G. Leoncini
University of Genoa, Italy.
R. Pontremoli
University of Genoa, Italy.
A number of epidemiological studies have reported an association between serum uric acid levels and a wide variety of high-risk conditions including hypertension, insulin resistance, and kidney and cerebro-cardiovascular disease. All things considered, serum uric acid may induce cardiovascular and kidney events both directly and indirectly by promoting other well-known mechanisms of damage. While asymptomatic hyperuricemia is currently not considered to be an indication for urate lowering therapy, there is growing evidence indicating a linear relationship between pharmacological reduction in serum uric acid and incidence of cardiovascular and renal events.

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F. Viazzi, University of Genoa
Department of Cardionephrology
G. Leoncini, University of Genoa
Department of Cardionephrology
R. Pontremoli, University of Genoa
Department of Cardionephrology

How to Cite

Viazzi, F., Leoncini, G., & Pontremoli, R. (2011). Cardiovascular and renal effects of hyperuricaemia and gout. Reumatismo, 63(4), 253–262. https://doi.org/10.4081/reumatismo.2011.253

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