https://doi.org/10.4081/reumatismo.2017.976

Mesenchimal stem cells: a possible role in the pathogenesis and treatment of spondyloarthritis

Vol. 69 No. 1 (2017)
Submitted: 8 February 2017
Accepted: 13 March 2017
Published: 22 May 2017
Spondyloarthritis, Mesenchimal stem cells, Pathogenesis, Treatment.
Abstract Views: 2232
PDF: 1397
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

F.M. Perrotta
Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy.
G. Guerra
Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy.
A. De Socio
Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy.
S. Scriffignano
Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy.
E. Lubrano
enniolubrano@hotmail.com
Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy.
Spondyloarthritis (SpAs) are a group of chronic inflammatory diseases that affect joints and enthesis with a possible involvement of other districts such as skin, eye and bowel. In SpAs, the inflammatory process could lead to both erosive damage (as in peripheral joint involvement of psoriatic arthritis), or bone formation (as in ankylosing spondylitis) with a reduction in function and quality of life. Recently, Mesenchimal stem cells (MSCs) transplant was used in different diseases, including autoimmune and inflammatory diseases, with the aim of repairing tissue damage, exploiting their regenerative capacity. However, MSCs also proved to have an immune-modulatory capacity due to their interaction with the cells of the immune system. The aim of this brief paper was to review the possible pathogenic role and the new perspective of MSCs use in SpAs.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
F.M. Perrotta, Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso
Dipartimento di Medicina e Scienze della Salute, MD
G. Guerra, Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso
Dipartimento di Medicina e Scienze della Salute, MD, PhD
A. De Socio, Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso
Dipartimento di Medicina e Scienze della Salute, MD
E. Lubrano, Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso
Dipartimento di Medicina e Scienze della Salute, MD, PhD

How to Cite

Perrotta, F., Guerra, G., De Socio, A., Scriffignano, S., & Lubrano, E. (2017). Mesenchimal stem cells: a possible role in the pathogenesis and treatment of spondyloarthritis. Reumatismo, 69(1), 1–8. https://doi.org/10.4081/reumatismo.2017.976

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Similar Articles

<< < 28 29 30 31 32 33 34 35 36 37 > >> 

You may also start an advanced similarity search for this article.