https://doi.org/10.4081/reumatismo.2016.917

A case of mandible Paget’s disease of the bone treated with intravenous neridronate

Vol. 68 No. 3 (2016)
Submitted: 8 August 2016
Accepted: 24 October 2016
Published: 16 December 2016
Paget’s disease of the bone, neridronate, mandible.
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Authors

A. Fassio
angelo.fassio@yahoo.it
Unit of Rheumatology, University of Verona, Italy.
L. Idolazzi
Unit of Rheumatology, University of Verona, Italy.
M. Rossini
Unit of Rheumatology, University of Verona, Italy.
O. Viapiana
Unit of Rheumatology, University of Verona, Italy.
D. Gatti
Unit of Rheumatology, University of Verona, Italy.
Paget’s disease of bone (PDB) is a focal disorder of osteoclasts, leading to chaotic bone remodelling, and it is characterized by the presence of focal areas of excessive bone formation alongside with areas of focal bone resorption. The typical radiographic feature is the cotton wool appearance. To date, bisphosphonates are the mainstay of the treatment. We hereby report the case of a young woman presenting with mandible PDB, with a relevant diagnostic delay and mistakenly treated for five years with chronic oral corticosteroids. After our evaluation, the patient received treatment with intravenous neridronate (an amino-bisphosphonate licensed in Italy for the treatment of this disease), with achievement of clinical remission.

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How to Cite

Fassio, A., Idolazzi, L., Rossini, M., Viapiana, O., & Gatti, D. (2016). A case of mandible Paget’s disease of the bone treated with intravenous neridronate. Reumatismo, 68(3), 154–158. https://doi.org/10.4081/reumatismo.2016.917

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