https://doi.org/10.4081/reumatismo.2025.1823
After what time interval are we justified to diagnose immune checkpoint inhibitor-mediated polymyalgia rheumatica?
Published: 3 March 2025
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Dear Editor,
the number of cases of cancer patients diagnosed as having immune checkpoint inhibitor-mediated polymyalgia rheumatica has been steadily rising in published reports. However, the lack of a validated scale or algorithm is still a relevant methodological limit in diagnosing this nosologic entity...
Hysa E, Casabella A, Gotelli E, Campitiello R, Schenone C, Genova C, et al. Polymyalgia rheumatica and giant cell arteritis induced by immune checkpoint inhibitors: a systematic literature review highlighting differences from the idiopathic forms. Autoimmun Rev 2024; 23: 103589.
DOI: https://doi.org/10.1016/j.autrev.2024.103589
Kostine M, Finckh A, Bingham CO, Visser K, Leipe J, SchulzeKoops H, et al. EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors. Ann Rheum Dis 2020; 80: 36-48.
DOI: https://doi.org/10.1136/annrheumdis-2020-217139
Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reaction. Clin Pharmacol Ther 1981; 30: 239-45.
DOI: https://doi.org/10.1038/clpt.1981.154
Manzo C, Natale M, Isetta M, Castagna A. Comment on: immune checkpoint inhibitor-mediated polymyalgia rheumatica versus primary polymyalgia rheumatica: comparison of disease characteristics and treatment requirement. Rheumatology 2025; 64: 900-1.
DOI: https://doi.org/10.1093/rheumatology/keae259
Manzo C, Isetta M. Back to the future: identification and classification of polymyalgia rheumatica and polymyalgia rheumatica-like syndromes following cancer immunotherapy with checkpoint inhibitors. Reumatologia 2021; 59: 62-3.
DOI: https://doi.org/10.5114/reum.2021.102600
How to Cite
Manzo, C., & Isetta, M. (2025). After what time interval are we justified to diagnose immune checkpoint inhibitor-mediated polymyalgia rheumatica?. Reumatismo. https://doi.org/10.4081/reumatismo.2025.1823
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