https://doi.org/10.4081/reumatismo.2024.1621

A focus on melorheostosis disease: a literature review and case report of femoral-acetabular impingement due to melorheostosis treated with surgical hip osteoplasty

Vol. 76 No. 1 (2024)
Submitted: 22 July 2023
Accepted: 25 October 2023
Published: 22 March 2024
Melorheostosis, bone rare disease, orthopedic surgery, bisphosphonate therapy, musculoskeletal rehabilitation
Abstract Views: 2246
PDF: 347
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Authors

M. Ruggiero
https://orcid.org/0000-0002-4894-9456
Physical and Rehabilitation Medicine 2, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
A. Conforti
alessandro.conforti@aslroma4.it
Local Health Unit Roma 4, Civitavecchia, Rome, Italy.
A. Culcasi
Technical and Rehabilitation Nursing Service, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
C. Mazzanti
https://orcid.org/0009-0005-4334-0181
Physical and Rehabilitation Medicine 2, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
G. Sibahi
Physical and Rehabilitation Medicine 2, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
N. Rani
Conservative Orthopaedic Surgery and Innovative Techniques, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
S. Sartini
Physical and Rehabilitation Medicine 2, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Objective. Melorheostosis is a rare, non-hereditary, benign bone disease characterized by abnormal bone growth. Generally, melorheostosis develops during childhood or adolescence and progresses gradually over time. This disease represents a true challenge to the physician because of its variability due to location, extension of the affected bone, and involvement of associated soft tissue. Pain management, physical therapy, and surgery may be recommended, depending on the individual case. This review aims to get an overview of the latest evidence relating to epidemiology, clinical and radiographic characteristics, diagnosis, and possible therapeutic strategies for melorheostosis and describe our experience through a clinical case.

Methods. We designed a comprehensive literature search on melorheostosis in MEDLINE (via Pubmed) up to April 2023 and reviewed reports published in international journals.

Results. The purpose is to highlight the importance of a multidisciplinary approach in the management of a rare disease such as melorheostosis. We discuss the role of different physicians, including genetists, rheumatologists, physiatrists, physical therapists, and orthopedic surgeons, in providing accurate diagnoses and effective treatments. We conducted a comprehensive review of the literature on the treatment of melorheostosis to support these findings. In addition, the article presents a case study of a patient suffering from melorheostosis, focusing on difficulties in reaching a correct diagnosis and attempts towards conservative and surgical interventions. The patient underwent hip arthroplasty, and the final result was an improvement in function and a reduction in pain.

Conclusions. Managing melorheostosis can be challenging, and there is no standardized treatment for this condition at the moment.

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How to Cite

Ruggiero, M., Conforti, A., Culcasi, A., Mazzanti, C., Sibahi, G., Rani, N., & Sartini, S. (2024). A focus on melorheostosis disease: a literature review and case report of femoral-acetabular impingement due to melorheostosis treated with surgical hip osteoplasty. Reumatismo, 76(1). https://doi.org/10.4081/reumatismo.2024.1621
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