Macrophage activation syndrome in a patient with systemic lupus erythematosus undergoing cyclophosphamide treatment: a case report

Submitted: 20 May 2023
Accepted: 30 June 2023
Published: 17 July 2023
Abstract Views: 930
PDF: 517
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Macrophage activation syndrome (MAS) is a disorder related to hemophagocytic lymphohistiocytosis and is a life-threatening complication of rheumatic diseases. The diagnosis is challenging because MAS symptoms are quite similar to those of many active autoimmune diseases or severe sepsis. We describe the case of a female patient with systemic lupus erythematosus that presented with symptoms suggesting acute decompensation of autoimmune disease and sepsis. She was later diagnosed with MAS. Despite an aggressive immunosuppressive treatment, she developed a fatal outcome.

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Citations

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How to Cite

Fioravante da Silveira, L., Zago, A. ., Zanchet, D., & Chemello, D. (2023). Macrophage activation syndrome in a patient with systemic lupus erythematosus undergoing cyclophosphamide treatment: a case report. Reumatismo, 75(2). https://doi.org/10.4081/reumatismo.2023.1597

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