https://doi.org/10.4081/reumatismo.2023.1539
Eosinophilic fasciitis in a young male auto mechanic exposed to organic solvents
Submitted: 1 December 2022
Accepted: 8 July 2023
Published: 18 September 2023
Accepted: 8 July 2023
Abstract Views: 964
PDF: 342
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
We report a case of eosinophilic fasciitis in a teenage auto mechanic who was most likely affected by occupational exposure to organic solvents, including the aromatic hydrocarbons benzene, trimethylbenzene, naphthalene, toluene, and xylene. The patient presented with an 8-month history of painful induration of his extremities and an abnormal gait. A deep excisional biopsy of the fascia was obtained, demonstrating subcutaneous fibrosis with perivascular and interstitial inflammation, with lymphocytes and plasma cells spilling into the sclerosed fascia, and focal fibrinoid necrosis. Treatment was begun with intravenous pulse doses of methylprednisolone, prednisone (20 mg daily), and subcutaneous methotrexate (25 mg weekly), and the patient’s painful induration had resolved and gait had normalized at the 6-month follow-up. Our case suggests that exposure to organic solvents could be implicated in the pathogenesis of eosinophilic fasciitis and highlights the importance of a thorough occupational history to prevent repeat exposures to potentially causative agents.
Mazori DR, Femia AN, Vleugels RA. Eosinophilic fasciitis: an updated review on diagnosis and treatment. Curr Rheumatol Rep 2017; 19: 74.
DOI: https://doi.org/10.1007/s11926-017-0700-6
Pinal-Fernandez I, Selva-O' Callaghan A, Grau JM. Diagnosis and classification of eosinophilic fasciitis. Autoimmun Rev 2014; 13: 379-82.
DOI: https://doi.org/10.1016/j.autrev.2014.01.019
Bischoff L, Derk CT. Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literature. Int J Dermatol 2008; 47: 29-35.
DOI: https://doi.org/10.1111/j.1365-4632.2007.03544.x
Pinal-Fernandez I, Callejas-Moraga EL, Roade-Tato ML, Simeon-Aznar CP. Groove sign in eosinophilic fasciitis. Lancet 2014; 384: 1774.
DOI: https://doi.org/10.1016/S0140-6736(14)60526-2
Jinnin M, Yamamoto T, Asano Y, Ishikawa O, Sato S, Takehara K, et al. Diagnostic criteria, severity classification and guidelines of eosinophilic fasciitis. J Dermatol 2018; 45: 881-90.
DOI: https://doi.org/10.1111/1346-8138.14160
Barragan-Martinez C, Speck-Hernandez CA, Montoya-Ortiz G, Mantilla RD, Anaya JM, Rojas-Villarraga A. Organic solvents as risk factor for autoimmune diseases: a systematic review and meta-analysis. PLoS One 2012; 7: e51506.
DOI: https://doi.org/10.1371/journal.pone.0051506
Ouchene L, Muntyanu A, Lavoue J, Baron M, Litvinov IV, Netchiporouk E. Toward understanding of environmental risk factors in systemic sclerosis [formula: see text]. J Cutan Med Surg 2021; 25: 188-204.
DOI: https://doi.org/10.1177/1203475420957950
Ohtsuka T. Organic solvent-induced myopathy simulating eosinophilic fasciitis and/or dermatomyositis. J Dermatol 2009; 36: 358-9.
DOI: https://doi.org/10.1111/j.1346-8138.2009.00653.x
Wang G, Cai P, Ansari GA, Khan MF. Oxidative and nitrosative stress in trichloroethene-mediated autoimmune response. Toxicology 2007; 229: 186-93.
DOI: https://doi.org/10.1016/j.tox.2006.10.014
Uzma N, Salar BM, Kumar BS, Aziz N, David MA, Reddy VD. Impact of organic solvents and environmental pollutants on the physiological function in petrol filling workers. Int J Environ Res Public Health 2008; 5: 139-46.
DOI: https://doi.org/10.3390/ijerph5030139
Lebeaux D, Frances C, Barete S, Wechsler B, Dubourg O, Renoux J, et al. Eosinophilic fasciitis (Shulman disease): new insights into the therapeutic management from a series of 34 patients. Rheumatology 2012; 51: 557-61.
DOI: https://doi.org/10.1093/rheumatology/ker366
How to Cite
Treichel, A., Zheng, D., Ranasinghe, G., Zeft, A., Bergfeld, W., & Bayart, C. (2023). Eosinophilic fasciitis in a young male auto mechanic exposed to organic solvents. Reumatismo, 75(3). https://doi.org/10.4081/reumatismo.2023.1539
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