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Pathergy-like reaction induced by laser hair removal in a patient with Behçet disease

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Behçet disease (BD) is a rare systemic vasculitis of unknown etiology, primarily characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. Pathergy test positivity is a nonspecific inflammatory response of the skin to trauma and supports the diagnosis. Recently, new inducers of pathergy reactions have been identified, for example, the placement of dental braces and laser hair removal. Our clinical case highlights the importance of thinking about this potential pathergy inducer in BD patients, to improve their quality of life and avoid complications.

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Citations

Sakane T, Takeno M, Suzuki N, Inaba G. Behçet's disease. N Engl J Med 1999; 341: 1284-91. DOI: https://doi.org/10.1056/NEJM199910213411707
Van de Ree-Pellikaan C, Kiewiet-Kemper RM, Tchetverikov I, Westerweel PE. Oral ulcerations after placement of orthodontic braces and skin pustules after laser hair removal: novel inducers of pathergy reactions in new-onset Behçet's disease. BMJ Case Rep 2016; 2016: bcr2014209208. DOI: https://doi.org/10.1136/bcr-2014-209208
Sequeira FF, Daryani D. The oral and skin pathergy test. Indian J Dermatol Venereol Leprol 2011; 77: 526-30. DOI: https://doi.org/10.4103/0378-6323.82399
Ergun T. Pathergy phenomenon. Front Med (Lausanne) 2021; 8: 639404. DOI: https://doi.org/10.3389/fmed.2021.639404
Boyvat A, Aygun M. A case report of pathergy-like reaction in a patient with Behçet's disease triggered by wax epilation. Ann Dermatol 2021; 33: 388-9. DOI: https://doi.org/10.5021/ad.2021.33.4.388

How to Cite

Nicolau, R., Martins Rocha, T., & Costa, L. (2023). Pathergy-like reaction induced by laser hair removal in a patient with Behçet disease. Reumatismo, 75(2). https://doi.org/10.4081/reumatismo.2023.1509

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