https://doi.org/10.4081/reumatismo.2022.1502
The vicious cycle of physical inactivity, fatigue and kinesiophobia in patients with fibromyalgia syndrome
Submitted: 24 May 2022
Accepted: 9 January 2023
Published: 21 March 2023
Accepted: 9 January 2023
Abstract Views: 1277
PDF: 748
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
This study aims to determine the association between fatigue, kinesiophobia, disease severity, and physical inactivity by comparing fibromyalgia syndrome (FMS) patients with healthy controls. Pain and fatigue are significant barriers to the participation in functional activities. Inactivity is a result of fatigue, but exercise is the foundation of FMS treatment. This case-control study included a total of 203 participants (107 patients with FMS and 96 healthy volunteers). The fibromyalgia impact questionnaire, the fatigue severity scale, the international physical activity questionnaire, and the Tampa scale for kinesiophobia were assessed. The FMS group scored significantly higher on the fatigue severity scale and kinesiophobia than the control group (p<0.001). Significantly lower metabolic task equivalent (MET) scale values were observed in the FMS group compared to the control group (p<0.001). The severity of fatigue and kinesiophobia correlated positively with the FMS impact questionnaire (p=0.001, r=0.621) and negatively with the MET scale (p=0.009, r= –0.287). Patients with FMS experience greater fatigue, kinesiophobia, and inactivity. As the severity of FMS worsens, so do disability, kinesiophobia, and fatigue. This study highlights the importance of breaking the cycle of fatigue and inactivity in the treatment of FMS.
Dailey DL, Frey Law LA, Vance CGT, Rakel BA, Merriwether EN, Darghosian L, et al. Perceived function and physical performance are associated with pain and fatigue in women with fibromyalgia. Arthritis Res Ther 2016;18:68.
Kratz AL, Schilling S, Goesling J, Williams DA. The PROMIS fatigueFM profile: a self-report measure of fatigue for use in fibromyalgia. Qual Life Res 2016;25:1803-13.
DOI: https://doi.org/10.1007/s11136-016-1230-9
Bennett RM, Russell J, Cappelleri JC, Bushmakin AG, Zlateva G, Sadosky A. Identification of symptom and functional domains that fibromyalgia patients would like to see improved: a cluster analysis. BMC Musculoskelet Disord 2010;11:134.
DOI: https://doi.org/10.1186/1471-2474-11-134
Vincent A, Benzo RP, Whipple MO, McAllister SJ, Erwin PJ, Saligan LN. Beyond pain in fibromyalgia: insights into the symptom of fatigue. Arthritis Res Ther 2013;15:221.
DOI: https://doi.org/10.1186/ar4395
Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P, et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res (Hoboken) 2010;62:600-10.
DOI: https://doi.org/10.1002/acr.20140
Andrade A, Vilarino GT, Sieczkowska SM, Coimbra DR, Bevilacqua GG, Steffens RAK. The relationship between sleep quality and fibromyalgia symptoms. J Health Psychol 2020;25:1176-86.
DOI: https://doi.org/10.1177/1359105317751615
Álvarez MC, Albuquerque MLL, Neiva HP, Cid L, Rodrigues F, Teixeira DS, et al. The multidimensional daily diary of fatigue-fibromyalgia-17 ıtems (MDF-Fibro-17): evidence from validity, reliability and transcultural ınvariance between Portugal and Brazil. J Clin Med 2020;9:2330.
DOI: https://doi.org/10.3390/jcm9082330
Estévez-López F, Maestre-Cascales C, Russell D, Álvarez-Gallardo IC, Rodriguez-Ayllon M, Hughes CM, et al. Effectiveness of exercise on fatigue and sleep quality in fibromyalgia: a systematic review and meta-analysis of randomized trials. Arch Phys Med Rehabil 2021;102:752-61.
DOI: https://doi.org/10.1016/j.apmr.2020.06.019
Couto N, Monteiro D, Cid L, Bento T. Effect of different types of exercise in adult subjects with fibromyalgia: a systematic review and meta-analysis of randomised clinical trials. Sci Rep 2022;12:10391.
DOI: https://doi.org/10.1038/s41598-022-14213-x
Albuquerque MLL, Monteiro D, Marinho DA, Vilarino GT, Andrade A, Neiva HP. Effects of different protocols of physical exercise on fibromyalgia syndrome treatment: systematic review and meta-analysis of randomized controlled trials. Rheumatol Int 2022;42:1893-908.
DOI: https://doi.org/10.1007/s00296-022-05140-1
Sanz-Baños Y, Pastor-Mira M, Lledó A, López-Roig S, Peñacoba C, Sánchez-Meca J. Do women with fibromyalgia adhere to walking for exercise programs to improve their health? Systematic review and meta-analysis. Disabil Rehabil 2018;40:2475-87.
DOI: https://doi.org/10.1080/09638288.2017.1347722
Dailey DL, Frey Law LA, Vance CG, Rakel BA, Merriwether EN, Darghosian L, et al. Perceived function and physical performance are associated with pain and fatigue in women with fibromyalgia. Arthritis Res Ther 2016;18:68.
DOI: https://doi.org/10.1186/s13075-016-0954-9
Silverman S, Sadosky A, Evans C, Yeh Y, Alvir JM, Zlateva G. Toward characterization and definition of fibromyalgia severity. BMC Musculoskelet Disord 2010;11:66.
DOI: https://doi.org/10.1186/1471-2474-11-66
Góes SM, Leite N, Shay BL, Homann D, Stefanello JM, Rodacki AL. Functional capacity, muscle strength and falls in women with fibromyalgia. Clin Biomech (Bristol, Avon) 2012;27:578-83.
DOI: https://doi.org/10.1016/j.clinbiomech.2011.12.009
Turk DC, Robinson JP, Burwinkle T. Prevalence of fear of pain and activity in patients with fibromyalgia syndrome. J Pain 2004;5:483-90.
DOI: https://doi.org/10.1016/j.jpain.2004.08.002
Burwinkle T, Robinson JP, Turk DC. Fear of movement: factor structure of the tampa scale of kinesiophobia in patients with fibromyalgia syndrome. J Pain 2005;6:384-91.
DOI: https://doi.org/10.1016/j.jpain.2005.01.355
Bennett R. The Fibromyalgia ımpact questionnaire (FIQ): a review of its development, current version, operating characteristics and uses. Clin Exp Rheumatol 2005;23:S154-62.
Acar S, Savci S, Keskinoğlu P, Akdeniz B, Özpelit E, Özcan Kahraman B, et al. Tampa scale of kinesiophobia for heart turkish version study: cross-cultural adaptation, exploratory factor analysis, and reliability. J Pain Res 2016;9:445-51.
DOI: https://doi.org/10.2147/JPR.S105766
Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 1989;46:1121-3.
DOI: https://doi.org/10.1001/archneur.1989.00520460115022
Gencay-Can A, Can SS. Validation of the Turkish version of the fatigue severity scale in patients with fibromyalgia. Rheumatol Int 2012;32:27-31.
DOI: https://doi.org/10.1007/s00296-010-1558-3
Lee PH, Macfarlane DJ, Lam TH, Stewart SM. Validity of the ınternational physical activity questionnaire short form (IPAQ-SF): a systematic review. Int J Behav Nutr Phys Act 2011;8:115.
DOI: https://doi.org/10.1186/1479-5868-8-115
International Physical Activity Scoring Protocol. Available from: https://sites.google.com/site/theipaq/scoring-protocol.
Saglam M, Arikan H, Savci S, Inal-Ince D, Bosnak-Guclu M, Karabulut E, et al. International physical activity questionnaire: reliability and validity of the Turkish version. Percept Mot Skills 2010;111:278-84.
DOI: https://doi.org/10.2466/06.08.PMS.111.4.278-284
KoÇyİĞİt BF, Akaltun MS. Kinesiophobia levels in fibromyalgia syndrome and the relationship between pain, disease activity, depression. Arch Rheumatol 2020;35:214-9.
DOI: https://doi.org/10.46497/ArchRheumatol.2020.7432
Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the multicenter criteria committee. Arthritis Rheum 1990;33:160-72.
DOI: https://doi.org/10.1002/art.1780330203
Joustra ML, Zijlema WL, Rosmalen JGM, Janssens KAM. Physical activity and sleep in chronic fatigue syndrome and fibromyalgia syndrome: associations with symptom severity in the general population cohort lifelines. Pain Res Manag 2018;2018:5801510.
DOI: https://doi.org/10.1155/2018/5801510
Correa-Rodríguez M, Mansouri-Yachou JE, Casas-Barragán A, Molina F, Rueda-Medina B, Aguilar-Ferrandiz ME. The Association of body mass ındex and body composition with pain, disease activity, fatigue, sleep and anxiety in women with fibromyalgia. Nutrients 2019;11:1193.
DOI: https://doi.org/10.3390/nu11051193
Sieczkowska SM, Vilarino GT, de Souza LC, Andrade A. Does physical exercise improve quality of life in patients with fibromyalgia? Ir J Med Sci 2020;189:341-7.
DOI: https://doi.org/10.1007/s11845-019-02038-z
Campos RP, Vázquez I, Vilhena E. Clinical, psychological and quality of life differences in fibromyalgia patients from secondary and tertiary healthcare. Eur J Pain 2021;25:558-72.
DOI: https://doi.org/10.1002/ejp.1694
Ma J, Zhang T, Li X, Chen X, Zhao Q. Effects of aquatic physical therapy on clinical symptoms, physical function, and quality of life in patients with fibromyalgia: a systematic review and meta-analysis. Physiother Theory Pract 2022:1-19.
DOI: https://doi.org/10.1080/09593985.2022.2119906
Ughreja RA, Venkatesan P, Balebail Gopalakrishna D, Singh YP. Effectiveness of myofascial release on pain, sleep, and quality of life in patients with fibromyalgia syndrome: a systematic review. Complement Ther Clin Pract 2021;45:101477.
DOI: https://doi.org/10.1016/j.ctcp.2021.101477
Polat M, Kahveci A, Muci B, Günendi Z, Kaymak Karataş G. The effect of virtual reality exercises on pain, functionality, cardiopulmonary capacity, and quality of life in fibromyalgia syndrome: a randomized controlled study. Games Health J 2021;10:165-73.
DOI: https://doi.org/10.1089/g4h.2020.0162
Samami E, Shahhosseini Z, Elyasi F. The effect of psychological ınterventions on the quality of life in women with fibromyalgia: a systematic review. J Clin Psychol Med Settings 2021;28:503-17.
DOI: https://doi.org/10.1007/s10880-021-09794-0
Vilarino GT, Branco JHL, de Souza LC, Andrade A. Effects of resistance training on the physical symptoms and functional capacity of patients with fibromyalgia: a systematic review and meta-analysis of randomized clinical trials. Ir J Med Sci 2022. doi: 10.1007/s11845-022-03205-5.
DOI: https://doi.org/10.1007/s11845-022-03205-5
Zhang KD, Wang LY, Zhang ZH, Zhang DX, Lin XW, Meng T, et al. Effect of exercise ınterventions on health-related quality of life in patients with fibromyalgia syndrome: a systematic review and network meta-analysis. J Pain Res 2022;15:3639-56.
DOI: https://doi.org/10.2147/JPR.S384215
How to Cite
Cigdem Karacay, B., Sahbaz, T., & Medin Ceylan, C. (2023). The vicious cycle of physical inactivity, fatigue and kinesiophobia in patients with fibromyalgia syndrome. Reumatismo, 74(4). https://doi.org/10.4081/reumatismo.2022.1502
Copyright (c) 2023 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
Similar Articles
- A. Alciati, P. Sgiarovello, F. Atzeni, P. Sarzi-Puttini, Psychiatric problems in fibromyalgia: clinical and neurobiological links between mood disorders and fibromyalgia , Reumatismo: Vol. 64 No. 4 (2012)
- M. A. Marie, R. E. Abu Khalil, H. M. Habib, Urinary CXCL10: a marker of nephritis in lupus patients , Reumatismo: Vol. 65 No. 6 (2013)
- L.C. de Souza, G. Torres Vilarino, A. Andrade, Does the volume of physical exercise influence sleep quality in patients with fibromyalgia? , Reumatismo: Early Access
- P. Galozzi, O. Negm, E. Greco, N. Alkhattabi, A. Gava, P. Sfriso, L. Fairclough, I. Todd, P. Tighe, L. Punzi, Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome , Reumatismo: Vol. 66 No. 4 (2014)
- F.M. Perrotta, A. Scarno, A. Carboni, V. Bernardo, M. Montepaone, E. Lubrano, A. Spadaro, Assessment of subclinical atherosclerosis in ankylosing spondylitis: correlations with disease activity indices , Reumatismo: Vol. 65 No. 3 (2013)
- B. Auvinet, D. Chaleil, Identification of subgroups among fibromyalgia patients , Reumatismo: Vol. 64 No. 4 (2012)
- G. Lapadula, A. Marchesoni, F. Salaffi, R. Ramonda, C. Salvarani, L. Punzi, L. Costa, F. Caso, D. Simone, G. Baiocchi, C. Scioscia, M. Di Carlo, R. Scarpa, G. Ferraccioli, Evidence-based algorithm for diagnosis and assessment in psoriatic arthritis: results by Italian DElphi in psoriatic Arthritis (IDEA) , Reumatismo: Vol. 68 No. 3 (2016)
- M. Lorenzin, A. Ortolan, P. Frallonardo, S. Vio, C. Lacognata, F. Oliviero, L. Punzi, R. Ramonda, Spine and sacroiliac joints on magnetic resonance imaging in patients with early axial spondyloarthritis: prevalence of lesions and association with clinical and disease activity indices from the Italian group of the SPACE study , Reumatismo: Vol. 68 No. 2 (2016)
- L. Magnani, A. Versari, D. Salvo, M. Casali, G. Germanò, R. Meliconi, L. Pulsatelli, D. Formisano, G. Bajocchi, N. Pipitone, L. Boiardi, C. Salvarani, Disease activity assessment in large vessel vasculitis , Reumatismo: Vol. 63 No. 2 (2011)
- M. Aouatef, B. Asma, H. Hajer, A. Charfeddine, B. Lamia, K. Taoufik, Work-related carpal tunnel syndrome treatment: a cross-sectional study among 106 patients , Reumatismo: Vol. 69 No. 2 (2017)
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
