https://doi.org/10.4081/reumatismo.2022.1489
Disseminated cutaneous herpes simplex infection after COVID-19 vaccination in a rheumatoid arthritis patient: a case report and review
Submitted: 16 March 2022
Accepted: 7 May 2022
Published: 13 September 2022
Accepted: 7 May 2022
Abstract Views: 1479
PDF: 788
Publisher's note
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Since COVID-19 vaccination started in December 2020, different side effects were reported. This case report describes the possibility of developing disseminated herpes simplex infection after COVID-19 vaccine in a patient with rheumatoid arthritis. In this case report, we describe a 63-year-old Iranian female. She was a known case of seronegative rheumatoid arthritis and presented with generalized papulo-pustular itchy and painful skin lesions which appeared about seven days after the second dose of Sinopharm BIBP COVID-19 vaccine (BIBP-CorV). A biopsy of the skin lesions revealed acantholysis, neutrophils, and enlarged keratinocytes with eosinophilic intra-nuclear inclusions. Findings were consistent with herpes simplex infection. She was successfully treated by acyclovir. Disseminated cutaneous herpes simplex infection may have been triggered by COVID-19 vaccination. Reactivation of herpes virus after COVID-19 vaccines was reported in both rheumatic patients and other individuals. Whether having an underlying autoimmune inflammatory disorder could be an additional risk factor is still unknown.
Polack FP, Thomas SJ, Kitchin N, et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. N Engl J Med. 2020 [Epub ahead of print].
Fathy RA, McMahon DE, Lee C, et al. Varicella‐zoster and herpes simplex virus reactivation post‐COVID‐19 vaccination: a review of 40 cases in an International Dermatology Registry. J Eur Acad Dermatol Venereol. 2021 [Epub ahead of print].
DOI: https://doi.org/10.1111/jdv.17646
Rodríguez-Jiménez P, Chicharro P, Cabrera L-M, et al. Varicella-Zoster virus reactivation after SARS-CoV-2 BNT162b2 mRNA vaccination: report of 5 cases. JAAD Case Rep. 2021; 12: 58-9.
DOI: https://doi.org/10.1016/j.jdcr.2021.04.014
Muhie OA, Adera H, Tsige E, Afework A. Herpes zoster following covaxin receipt. Int Med Case Rep J. 2021; 14: 819.
DOI: https://doi.org/10.2147/IMCRJ.S345288
Shah S, Baral B, Chamlagain R, et al. Reactivation of herpes zoster after vaccination with an inactivated vaccine: A case report from Nepal. Clin Case Rep. 2021; 9: e05188.
DOI: https://doi.org/10.1002/ccr3.5188
Atiyat R, Elias S, Kiwan C, et al. Varicella-Zoster virus reactivation in AIDS patient after Pfizer-BioNTech COVID-19 vaccine. Cureus. 2021; 13(12). [Epub ahead of print].
DOI: https://doi.org/10.7759/cureus.20145
Bostan E, Yalici-Armagan B. Herpes zoster following inactivated COVID-19 vaccine: a coexistence or coincidence? J Cosmet Dermatol. 2021 [Epub ahead of print].
DOI: https://doi.org/10.1111/jocd.14035
Furer V, Zisman D, Kibari A, et al. Herpes zoster following BNT162b2 mRNA Covid-19 vaccination in patients with autoimmune inflammatory rheumatic diseases: a case series. Rheumatology (Oxford, England). 2021 [Epub ahead of print].
DOI: https://doi.org/10.1093/rheumatology/keab345
Maranini B, Ciancio G, Cultrera R, Govoni M. Herpes zoster infection following mRNA COVID-19 vaccine in a patient with ankylosing spondylitis. Reumatismo. 2021; 73: 174-6.
DOI: https://doi.org/10.4081/reumatismo.2021.1445
How to Cite
Mohamadzadeh, D., Assar, S., Pournazari, M., Soufivand, P., & Danaei, S. (2022). Disseminated cutaneous herpes simplex infection after COVID-19 vaccination in a rheumatoid arthritis patient: a case report and review. Reumatismo, 74(2). https://doi.org/10.4081/reumatismo.2022.1489
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