https://doi.org/10.4081/reumatismo.2021.1431
Biclonal gammopathy of undetermined significance in a patient with systemic lupus erythematosus and antiphospholipid syndrome
Submitted: 17 May 2021
Accepted: 11 November 2021
Published: 7 February 2022
Accepted: 11 November 2021
Abstract Views: 5582
PDF: 565
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The case of a patient suffering from systemic lupus erythematosus with associated antiphospholipid antibody syndrome is described. In this patient, on protein electrophoresis, two monoclonal immunoglobulin G λ and k peaks were seen, defining a condition of biclonal gammopathy of undetermined significance (BGUS). This condition is extremely rare, especially in chronic inflammatory rheumatic diseases. The criteria of a BGUS are defined. We also underline how this condition can be the expression of a concomitant unrecognized cancer, a possible amyloidosis or an infectious process.
Gastelum-Cano JM, Fragoso-Flores J, Noffal-Nuno VM, et al. An unusual pattern in serum protein electrophoresis to take in mind: a case report. Prac Lab Med. 2021; 24: e00200.
DOI: https://doi.org/10.1016/j.plabm.2020.e00200
Mullikin TC, Rajkumar SV, Dispenzieri A, et al. Clinical characteristics and outcomes in biclonal gammopathies. Am J Hematol. 2016; 91: 473-5.
DOI: https://doi.org/10.1002/ajh.24319
Garcia-Garcia P, Enciso-Alvarez K, Diaz-Espada F, et al. Biclonal gammopathies: retrospective study of 47 patients. Rev Clin Esp. 2015; 215: 18-24.
DOI: https://doi.org/10.1016/j.rceng.2014.07.004
Laganà B, Podestà E, Picchianti Diamanti A, et al. Schnitzler’s syndrome with biclonal gammopathy successfully treated with hydroxychloroquine and low dose steroids. Clin Exp Rheumatol. 2008; 26: 1161.
Castro I, Arroyo C, Yanez V, et al. Multiple myeloma in systemic lupus erythematosus. Report of two cases. Rev Med Chil. 2018; 146: 670-4.
DOI: https://doi.org/10.4067/s0034-98872018000500670
Nagashima T, Muroi K, Kawano-Yamamoto C, et al. Paraproteinemia after hematopoietic stem cell transplantation. Leuk Lymphomas. 2004; 45: 135-7.
DOI: https://doi.org/10.1080/1042819031000139729
Bruzzese V. Monoclono nella cancro-cirrosi. Clin Ter. 1989; 131: 41-3.
Westerman R, Zobbe K, Cordtz R, et al. Increased cancer risk in patient with cutaneous lupus erythematosus and systemic lupus erythematosus compared with the general population: a Danish nationwide cohort study. Lupus. 2021 [Epub ahead of print].
DOI: https://doi.org/10.1177/0961203321990106
Chen C, Sun C. Multifocal head and neck amyloidosis as a diagnostic clue of systemic lupus erythematosus (SLE): a case report. Medicine (Baltimore). 2019; 98: e16830.
DOI: https://doi.org/10.1097/MD.0000000000016830
Chenng WI, Leung VKS, Luke ISL, et al. Splenic tuberculosis associated with monoclonal gammopathy of undetermined significance and pericarditis. Hong Kong Med J. 2009; 15: 291.
How to Cite
Bruzzese, V., Scolieri, P., & Pepe, J. (2022). Biclonal gammopathy of undetermined significance in a patient with systemic lupus erythematosus and antiphospholipid syndrome. Reumatismo, 73(4). https://doi.org/10.4081/reumatismo.2021.1431
Copyright (c) 2021 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
Similar Articles
- U. Fiocco, P. Sfriso, F. Oliviero, F. Sovran, E. Scagliori, E. Pagnin, M. Vezzù, L. Cozzi, C. Botsios, R. Nardacchione, A. Di Maggio, L. Rubaltelli, C. Giacometti, F. Calabrese, S. Todesco, Intra-articular etanercept treatment for severe diffuse pigmented villonodular knee synovitis , Reumatismo: Vol. 58 No. 4 (2006)
- A. Trotta, A. Corrado, M.F. Soragnese, N. Santoro, F.P. Cantatore, Adult Scheuermann’s disease as cause of mechanic dorsalgia , Reumatismo: Vol. 60 No. 1 (2008)
- E. Özduran, V. Hanci, Evaluating the readability, quality and reliability of online information on Behçet’s disease , Reumatismo: Vol. 74 No. 2 (2022)
- R. Tanten Zabaleta, J. Marín, J.B. Zacariaz Hereter, J. Maritano, M. Fullana, N. Alvarado, E.R. Soriano, J.E. Rosa, Clinical utility of lung ultrasound for the detection of interstitial lung disease in patients with rheumatoid arthritis , Reumatismo: Early Access
- N. Franzolini, L. Quartuccio, G. De Marchi, S. De Vita, Efficacy of immunosoppressive therapy and steroid sparing effect in interstitial lung disease associated to antisynthetase syndrome , Reumatismo: Vol. 59 No. 3 (2007)
- M. Parodi, L. Bensi, T. Maio, G.S. Mela, M.A. Cimmino, Comorbidities in rheumatoid arthritis: analysis of hospital discharge records , Reumatismo: Vol. 57 No. 3 (2005)
- G. Lapadula, Biologic therapy with anti-TNFa in spondyloarthritides and other autoimmune diseases , Reumatismo: Vol. 57 No. s4 (2005)
- Richard Trèves, Dupuytren’s disease , Reumatismo: Vol. 58 No. 3 (2006)
- L. Cantarini, A. Vitale, O.M. Lucherini, I. Muscari, F. Magnotti, G. Brizi, B. Frediani, G.D. Sebastiani, M. Galeazzi, D. Rigante, Childhood versus adulthood-onset autoinflammatory disorders: myths and truths intertwined , Reumatismo: Vol. 65 No. 2 (2013)
- S. Gülle, A. Çelik, M. Birlik, O. Yılmaz, Skin and lung fibrosis induced by bleomycin in mice: a systematic review , Reumatismo: Vol. 76 No. 1 (2024)
<< < 21 22 23 24 25 26 27 28 29 30 > >>
You may also start an advanced similarity search for this article.
