https://doi.org/10.4081/reumatismo.2020.1297
Case report of polymyalgia rheumatica in a male patient with three different neoplasms treated with pembrolizumab
Submitted: 11 May 2020
Accepted: 18 July 2020
Published: 19 November 2020
Accepted: 18 July 2020
Abstract Views: 1045
PDF: 641
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
In this manuscript we aim to describe a particular case of a 63 years-old man who developed three different malignancies (one was a rare case of breast cancer) among nearly five years. In particular, for the diagnosis of melanoma, he was treated with pembrolizumab, a PD-1 inhibitor. After few months of treatment with pembrolizumab, the patient reported the onset of musculoskeletal symptoms such as inflammatory pain at the shoulders and morning stiffness, with raised CRP and ESR and imaging evidence of bursitis and tenosynovitis. A polymyalgia-like syndrome was diagnosed. Understanding if these manifestations are linked to the use of pembrolizumab or to a paraneoplastic syndrome, and how to manage the patient, was the real challenge.
How to Cite
Perrotta, F., Scriffignano, S., Fatica, M., Specchia, M., & Lubrano, E. (2020). Case report of polymyalgia rheumatica in a male patient with three different neoplasms treated with pembrolizumab. Reumatismo, 72(3), 178–181. https://doi.org/10.4081/reumatismo.2020.1297
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