https://doi.org/10.4081/reumatismo.2020.1296
Efficacy of gluten-free diet in patients with rheumatoid arthritis
Accepted: 23 September 2020
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Recent research has increasingly shown that depending on the foods we eat, gut flora may be affected by an inflammatory or anti-inflammatory response, thus playing an important role in inflammatory autoimmune diseases, such as rheumatoid arthritis or gastroenterological disorders. Gluten seems to be a glycoprotein with a clinically relevant inflammatory effect. Several observational studies and anecdotal cases reported a correlation between gluten and various diseases, including autoimmune diseases, such as rheumatoid arthritis. This study aimed to evaluate whether gluten-free diet could be effective in controlling inflammation and ongoing rheumatoid arthritis symptoms. We report 4 cases of patients with long-standing rheumatoid arthritis with no response to several conventional and biotechnological drugs, treated with a gluten-free diet concurrently with the drug therapy. Our patients presented different degrees of response to the diet, in terms of disease remission and improvement of symptoms. Our cases confirm that a gluten-free diet may improve symptoms of rheumatoid arthritis, even in patients resistant to conventional drug therapies.
How to Cite
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
Similar Articles
- N. Ughi, T. Schioppo, I. Scotti, V. Merlino, A. Murgo, O. De Lucia, B. Fautrel, F. Guillemin, R. Christensen, F. Ingegnoli, Translation and cross-cultural adaptation into Italian of the self-administered FLARE-RA questionnaire for rheumatoid arthritis , Reumatismo: Vol. 72 No. 1 (2020)
- G.L. Erre, A. Tocco, R. Faedda, A. Cossu, A. Carcassi, Diagnostic and prognostic value of antibodies to cyclic citrullinated peptide (Anti-CCP) in rheumatoid arthritis , Reumatismo: Vol. 56 No. 2 (2004)
- P. Quattrocchi, A. Barrile, D. Bonanno, L. Giannetto, M. Patafi, V. Tigano, B. Ferlazzo, The role of anti-nucleosome antibodies in systemic lupus erythematosus. Results of a study of patients with systemic lupus erythematosus and other connective tissue diseases , Reumatismo: Vol. 57 No. 2 (2005)
- F. Salaffi, C.M. Vaccaro, T. Manacorda, L. Pardini, C.M. Montecucco, Socio-demographic aspects and therapeutic pathways in patients with rheumatoid arthritis in Italy , Reumatismo: Vol. 61 No. 3 (2009)
- E. Marcucci, E. Bartoloni, A. Alunno, M.C. Leone, G. Cafaro, F. Luccioli, V. Valentini, E. Valentini, G.M.C. La Paglia, A.F. Bonifacio, R. Gerli, Extra-articular rheumatoid arthritis , Reumatismo: Vol. 70 No. 4 (2018)
- L. Quartuccio, M. Fabris, G. Ferraccioli, B Lymphocyte stimulator (BLyS) and monocytes: possible role in autoimmune diseases with a particular reference to rheumatoid arthritis , Reumatismo: Vol. 56 No. 3 (2004)
- M. Carotti, F. Salaffi, M. Mangiacotti, A. Cerioni, G.M. Giuseppetti, W. Grassi, Atherosclerosis in rheumatoid arthtritis: the role of high-resolution B mode ultrasound in the measurement of the arterial intima-media thickness , Reumatismo: Vol. 59 No. 1 (2007)
- D. Bonanno, R. Fedele, P. Minciullo, P. Quattrocchi, B. Ferlazzo, Idiopathic hypereosinophilic syndrome associated with rheumatoid arthritis A case report , Reumatismo: Vol. 55 No. 3 (2003)
- B. Seriolo, A. Sulli, B. Burroni, M. Cutolo, Rheumatoid arthritis and atherosclerosis , Reumatismo: Vol. 55 No. 3 (2003)
- M. Fabris, E. Di Poi, S. Sacco, G. Damante, L. Sinigaglia, G. Ferraccioli, TNF-α gene polymorphisms in rheumatoid arthritis patients treated with anti-TNF-α agents: preliminary results , Reumatismo: Vol. 54 No. 1 (2002)
<< < 15 16 17 18 19 20 21 22 23 24 > >>
You may also start an advanced similarity search for this article.
