https://doi.org/10.4081/reumatismo.2020.1274
Severe bullous systemic lupus erythematosus successfully treated with low dose rituximab: a case report from sub-Saharan Africa
Submitted: 20 February 2020
Accepted: 29 April 2020
Published: 23 July 2020
Accepted: 29 April 2020
Abstract Views: 882
PDF: 571
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Bullous systemic lupus erythematosus (BSLE) is a blistering skin condition occurring in lupus patients. Although cutaneous manifestations are common in lupus (59-85%), BSLE is rare, affecting <5% of lupus patients with very few reported cases among Africans. Dapsone is effective in mild to moderate cases, but off-label standard-dose rituximab (1,000 mg 2 weeks apart) has led to good outcomes in refractory cases. We report the case of a 39-yearold African lady with BSLE, who was successfully treated with low-dose rituximab (500 mg 2 weeks apart), healing her skin lesions at one year post-treatment. Low-dose rituximab may be as effective as standard dosing for the treatment of severe bullous SLE and is recommended in low resource settings.
How to Cite
Akpabio, A., & Otike-Odibi, B. (2020). Severe bullous systemic lupus erythematosus successfully treated with low dose rituximab: a case report from sub-Saharan Africa. Reumatismo, 72(2), 115–119. https://doi.org/10.4081/reumatismo.2020.1274
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
Similar Articles
- M.C. Abdulla, Spontaneous soft tissue haemorrhage in systemic lupus erythematosus , Reumatismo: Vol. 68 No. 4 (2016)
- S. El Aoud, F. Frikha, M. Snoussi, R. Ben Salah, Z. Bahloul, Bilateral ptosis as a presenting feature of primary hypertrophic osteoarthropathy (pachydermoperiostosis): a case report , Reumatismo: Vol. 66 No. 3 (2014)
- M. Bellan, M. Pirisi, G. Bellomo, P.P. Sainaghi, A case of false positive Troponin I in a patient affected by cryoglobulinemic vasculitis , Reumatismo: Vol. 69 No. 1 (2017)
- B. Palterer, G. Vitiello, D. Cammelli, First report of anti-TIF1γ dermatomyositis in a patient with myelodysplastic syndrome , Reumatismo: Vol. 69 No. 2 (2017)
- M. Varenna, F. Bertoldo, M. Di Monaco, A. Giusti, G. Martini, M. Rossini, On behalf of SIOMMMS, Endorsed by SIR, Safety profile of drugs used in the treatment of osteoporosis: a systematical review of the literature , Reumatismo: Vol. 65 No. 4 (2013)
- W.A. Wan Asyraf, M.S. Mohd Shahrir, W. Asrul, A.W. Norasyikin, O. Hanita, W.Y. Kong, M.T. Azmi, The association between serum prolactin levels and interleukin-6 and systemic lupus erythematosus activity , Reumatismo: Vol. 70 No. 4 (2018)
- L. Bazzichi, D. Biasi, E. Tinazzi, M. Muratore, R. Pellerito, R. Russo, M. Corsaro Santi, P. De Sandre, O. Epis, M. Granata, B. Kroegler, C. Meschini, F. Versace, C. Astolfi, Safety of rituximab in the routine treatment of rheumatoid arthritis in Italy in patients refractory to anti-TNFa drugs: results from the observational retrospective-prospective RUBINO study , Reumatismo: Vol. 66 No. 3 (2014)
- H.K. Aggarwal, D. Jain, A. Mittal, G. Dabas, Isolated oculocutaneous sarcoidosis in a teenage male: a rare case report , Reumatismo: Vol. 68 No. 2 (2016)
- E. Shahi, C. Donati, M. Gattinara, I. Pontikaki, V. Gerloni, Primary Sjögren syndrome: report of a 10 years old girl with local edema and positivity of anti SS-A and anti SS-B autoantibodies , Reumatismo: Vol. 63 No. 2 (2011)
- S. Warwas, C. Specker, M. Jäger, S. Landgraeber, Arthroscopic synovectomy and radiosynoviorthesis: a treatment option for recurrent arthritis symptoms in patients with pachydermoperiostosis , Reumatismo: Vol. 65 No. 2 (2013)
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
