https://doi.org/10.4081/reumatismo.2020.1274
Severe bullous systemic lupus erythematosus successfully treated with low dose rituximab: a case report from sub-Saharan Africa
Accepted: 29 April 2020
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Bullous systemic lupus erythematosus (BSLE) is a blistering skin condition occurring in lupus patients. Although cutaneous manifestations are common in lupus (59-85%), BSLE is rare, affecting <5% of lupus patients with very few reported cases among Africans. Dapsone is effective in mild to moderate cases, but off-label standard-dose rituximab (1,000 mg 2 weeks apart) has led to good outcomes in refractory cases. We report the case of a 39-yearold African lady with BSLE, who was successfully treated with low-dose rituximab (500 mg 2 weeks apart), healing her skin lesions at one year post-treatment. Low-dose rituximab may be as effective as standard dosing for the treatment of severe bullous SLE and is recommended in low resource settings.
How to Cite
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
Similar Articles
- D.C. Fernández Ávila, M. Diehl, A.M. Degrave, M. Buttazzoni, T. Pereira, M.A. Aguirre, A.L. Basquiera, M. Scolnik, Voriconazole-induced periostitis , Reumatismo: Vol. 73 No. 1 (2021)
- G. El Hasbani, A. Jawad, I. Uthman, Axial and peripheral spondyloarthritis triggered by sars-cov-2 infection: a report of two cases , Reumatismo: Vol. 73 No. 1 (2021)
- M. Polastri, G.M. Paganelli, G. Dolci, E. Di Ciaccio, I. Prediletto, Musculoskeletal syndrome treated with global postural re-education in double-redo lung transplantation: a case report with an 8-month follow-up , Reumatismo: Vol. 74 No. 1 (2022)
- H. Olaosebikan, A. Azenabor, R. Akintayo, O. Adelowo, A. Ogbera, A. Brodie-Mends, Spectrum of musculoskeletal disorders in Nigerians with types 2 diabetes mellitus: prevalence and predictors , Reumatismo: Vol. 71 No. 4 (2019)
- P. Marson, R. Rondinone, M. Vicarioto, Malar rash in a painting by Jean-Baptiste Siméon Chardin (1699-1779) , Reumatismo: Vol. 53 No. 2 (2001)
- Irene Pontikaki, Valeria Gerloni, Maurizio Gattinara, Alfredomaria Lurati, Alessandra Salmaso, Gabriele De Marco, Barbara Teruzzi, Elisabetta Valcamonica, Flavio Fantini, Side effects of anti-TNFa therapy in juvenile idiopathic arthritis , Reumatismo: Vol. 58 No. 1 (2006)
- E. Boninsegna, A. Fassio, M. Testoni, D. Gatti, O. Viapiana, G. Mansueto, M. Rossini, Radiological features of knee joint synovial chondromatosis , Reumatismo: Vol. 71 No. 2 (2019)
- R. Assari, P. Sadeghi, A. Mirmohammadsadeghi, F. Ebadi, V. Ziaee, Macrophage activation syndrome as a complication of rheumatologic disorders, a report from Iran , Reumatismo: Vol. 71 No. 4 (2019)
- E. Conticini, A. Negro, L. Magnani, R. Ugolini, B. Atienza-Mateo, B. Frediani, C. Salvarani, Gitelman syndrome associated with chondrocalcinosis and severe neuropathy: a novel heterozygous mutation in SLC12A3 gene , Reumatismo: Vol. 72 No. 1 (2020)
- R. Tirri, D. Capocotta, Incidental papillary thyroid cancer diagnosis in patient with adult-onset Still’s disease-like manifestations , Reumatismo: Vol. 71 No. 1 (2019)
<< < 15 16 17 18 19 20 21 22 23 24 > >>
You may also start an advanced similarity search for this article.
