Infliximab in the treatment of Budd-Chiari syndrome in Behçet’s disease

Submitted: 1 May 2018
Accepted: 17 July 2019
Published: 24 October 2019
Abstract Views: 1231
PDF: 763
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Behçet’s disease is a chronic autoinflammatory disorder that usually presents with recurrent oral and genital ulcers, uveitis, skin lesions and arthritis. Any organ, however, can be involved and in a subgroup of patients the large vascular lesions are the predominant feature (vasculo-Behçet disease). We report a case of a 27-yearold man with Behçet’s disease who developed Budd-Chiari syndrome while on immunosuppressive therapy. Infliximab resulted in a rapid and total clinical remission. Literature data have shown that antitumor necrosis factor alpha (anti-TNF-α) agents including infliximab can suppress disease activity but there is no long-term experience on tapering and/or discontinuation of treatment under clinical remission. Our case supports the use of infliximab in vasculo-Behçet patients.

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How to Cite

Santos, L., Rigueira, J., & Vilas, A. (2019). Infliximab in the treatment of Budd-Chiari syndrome in Behçet’s disease. Reumatismo, 71(3), 163–165. https://doi.org/10.4081/reumatismo.2019.1153

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