https://doi.org/10.4081/reumatismo.2019.1153
Infliximab in the treatment of Budd-Chiari syndrome in Behçet’s disease
Submitted: 1 May 2018
Accepted: 17 July 2019
Published: 24 October 2019
Accepted: 17 July 2019
Abstract Views: 1231
PDF: 763
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Behçet’s disease is a chronic autoinflammatory disorder that usually presents with recurrent oral and genital ulcers, uveitis, skin lesions and arthritis. Any organ, however, can be involved and in a subgroup of patients the large vascular lesions are the predominant feature (vasculo-Behçet disease). We report a case of a 27-yearold man with Behçet’s disease who developed Budd-Chiari syndrome while on immunosuppressive therapy. Infliximab resulted in a rapid and total clinical remission. Literature data have shown that antitumor necrosis factor alpha (anti-TNF-α) agents including infliximab can suppress disease activity but there is no long-term experience on tapering and/or discontinuation of treatment under clinical remission. Our case supports the use of infliximab in vasculo-Behçet patients.
How to Cite
Santos, L., Rigueira, J., & Vilas, A. (2019). Infliximab in the treatment of Budd-Chiari syndrome in Behçet’s disease. Reumatismo, 71(3), 163–165. https://doi.org/10.4081/reumatismo.2019.1153
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