https://doi.org/10.4081/reumatismo.2018.1084
Histopathology of the gut in rheumatic diseases
Accepted: 27 June 2018
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity to non-self-antigens. Various evidence indicates that intestinal inflammation occurs in patients with rheumatic diseases. In many rheumatic diseases intestinal inflammation appears to be linked to dysbiosis and possibly represents the common denominator in the pathogenesis of different rheumatic diseases. The continuative interaction between dysbiosis and the intestinal immune system may lead to the aberrant activation of immune cells that can re-circulate from the gut to the sites of extraintestinal inflammation as observed in patients with ankylosing spondylitis. The exact contribution of genetic factors in the development of intestinal inflammation in rheumatic diseases needs to be clarified.
How to Cite
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
Similar Articles
- R. Talotta, A. Berzi, F. Atzeni, D. Dell'Acqua, P. Sarzi Puttini, D. Trabattoni, Evaluation of Th9 lymphocytes in peripheral blood of rheumatoid arthritis patients and correlation with anti-tumor necrosis factor therapy: results from an in vitro pivotal study , Reumatismo: Vol. 68 No. 2 (2016)
- A. Fassio, L. Idolazzi, M. Rossini, O. Viapiana, D. Gatti, A case of mandible Paget’s disease of the bone treated with intravenous neridronate , Reumatismo: Vol. 68 No. 3 (2016)
- N. Bassi, R. Luisetto, A. Ghirardello, M. Gatto, B. Bottazzi, Y. Shoenfeld, L. Punzi, A. Doria, Vaccination of mice for research purpose: alum is as effective as and safer than complete Freund adjuvant , Reumatismo: Vol. 64 No. 6 (2012)
- P. Marson, G. Pasero, Some historical remarks on microcrystalline arthritis (gout and chondrocalcinosis) , Reumatismo: Vol. 63 No. 4 (2011): Special issue • Microcrystalline Arthritis
- G. Lapadula, G. Ferraccioli, C. Ferri, L. Punzi, F. Trotta, GISEA: an Italian biological agents registry in rheumatology , Reumatismo: Vol. 63 No. 3 (2011)
- A.B. Rasheed, M.S. Daoud, F.I. Gorial, Diagnostic utility of serum melatonin levels in systemic lupus erythematosus: a case-control study , Reumatismo: Vol. 69 No. 4 (2017)
- G. Pasero, P. Marson, A short history of anti-rheumatic therapy - VI. Rheumatoid arthritis drugs , Reumatismo: Vol. 63 No. 2 (2011)
- S. Maddali Bongi, A. Del Rosso, M. Matucci Cerinic, Rheumatologic rehabilitation: towards recommendations , Reumatismo: Vol. 66 No. 3 (2014)
- P. Quattrocchi, A. Barrile, D. Bonanno, L. Giannetto, M. Patafi, V. Tigano, B. Ferlazzo, The role of anti-nucleosome antibodies in systemic lupus erythematosus. Results of a study of patients with systemic lupus erythematosus and other connective tissue diseases , Reumatismo: Vol. 57 No. 2 (2005)
- S. D'Angelo, C. Palazzi, I. Olivieri, Psoriatic arthritis: treatment strategies using biologic agents , Reumatismo: Vol. 64 No. 2 (2012)
<< < 3 4 5 6 7 8 9 10 11 12 > >>
You may also start an advanced similarity search for this article.
