https://doi.org/10.4081/reumatismo.2018.1057
Histopathology of the synovial tissue: perspectives for biomarker development in chronic inflammatory arthritides
Submitted: 5 August 2017
Accepted: 3 November 2017
Published: 3 October 2018
Accepted: 3 November 2017
Abstract Views: 1635
PDF: 1134
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The histopathological and molecular analysis of the synovial tissue has contributed to fundamental advances in our comprehension of arthritis pathogenesis and of the mechanisms of action of currently available treatments. On the other hand, its exploitation in clinical practice for diagnostic or prognostic purposes as well as for the prediction of treatment response to specific disease-modifying anti-rheumatic drugs is still limited. In this review, we present an overview of recent advances in the field of synovial tissue research with specific reference to the methods for synovial tissue collection, approaches to synovial tissue analysis and current perspectives for the exploitation of synovial tissue-derived biomarkers in chronic inflammatory arthritides.
How to Cite
Manzo, A., Bugatti, S., Caporali, R., & Montecucco, C. (2018). Histopathology of the synovial tissue: perspectives for biomarker development in chronic inflammatory arthritides. Reumatismo, 70(3), 121–132. https://doi.org/10.4081/reumatismo.2018.1057
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