https://doi.org/10.4081/reumatismo.2018.1051

Histopathology of the muscle in rheumatic diseases

Vol. 70 No. 3 (2018): Monographic issue on Histopathology in Rheumatic Diseases
Submitted: 31 July 2017
Accepted: 3 November 2017
Published: 3 October 2018
Myositis, Muscle, Muscular biopsy, Histopathology.
Abstract Views: 1316
PDF: 1191
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Authors

S. Barsotti
simone.barsotti.pisa@gmail.com
http://orcid.org/0000-0002-4864-4505
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa; Department of Medical Biotechnologies, University of Siena, Italy.
A. Tripoli
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
L.E. Pollina
Pathology Department, University of Pisa Medical School Hospital, Pisa, Italy.
M. Mosca
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
R. Neri
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

The presence of muscular symptoms is common in rheumatological clinical practice, but often the differential diagnosis between muscular involvement in connective tissue diseases, vasculitis and drug-induced myopathy may be difficult. In addition to clinical assessment, laboratory analysis and instrumental examinations, muscle biopsy may help to clarify the diagnosis in patients with muscular involvement. The purpose of this review is to provide a critical analysis of the current medical literature on muscular histopathology, to help clinicians to identify when to perform muscular biopsy and to provide a practical guide to a better understanding of the pathology report. Moreover, we provide an overview of the muscular involvement and the most common histopathological findings in rheumatic diseases.

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S. Barsotti, Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa; Department of Medical Biotechnologies, University of Siena
Rheumatology unit, university of Pisa, Italy

How to Cite

Barsotti, S., Tripoli, A., Pollina, L., Mosca, M., & Neri, R. (2018). Histopathology of the muscle in rheumatic diseases. Reumatismo, 70(3), 133–145. https://doi.org/10.4081/reumatismo.2018.1051

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