https://doi.org/10.4081/reumatismo.2017.1007

Demyelinating syndrome in SLE: review of different disease subtypes and report of a case series

Vol. 69 No. 4 (2017)
Submitted: 5 May 2017
Accepted: 4 August 2017
Published: 21 December 2017
Systemic lupus erythematosus, Demyelinating syndrome, Neuropsychiatric lupus, Magnetic resonance.
Abstract Views: 2791
PDF: 1589
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

E. Chessa
elis.chessa@gmail.com
Rheumatology Unit, University Clinic AOU of Cagliari, Italy.
M. Piga
Rheumatology Unit, University Clinic AOU of Cagliari, Italy.
A. Floris
Rheumatology Unit, University Clinic AOU of Cagliari, Italy.
A. Mathieu
Rheumatology Unit, University Clinic AOU of Cagliari, Italy.
A. Cauli
Rheumatology Unit, University Clinic AOU of Cagliari, Italy.
Demyelinating syndrome (DS) is a rare manifestation of systemic lupus erythematosus (SLE) (1%) with high clinical heterogeneity and potentially severe prognosis. It can represent a diagnostic and therapeutic challenge for clinicians. A recent study described 5 different patterns of demyelinating disease presentation, characterised by specific clinical, laboratory and brain and spine magnetic resonance imaging abnormalities: 1) neuromyelitis optica; 2) neuromyelitis optica spectrum disorders; 3) DS prevalently involving the brain; 4) DS prevalently involving the brainstem; 5) clinically isolated syndrome. In this review we briefly discuss typical characteristics of each DS presentation in SLE and we describe 5 illustrative clinical cases, one for each subset of DS, considering both diagnostic and therapeutic options.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC

How to Cite

Chessa, E., Piga, M., Floris, A., Mathieu, A., & Cauli, A. (2017). Demyelinating syndrome in SLE: review of different disease subtypes and report of a case series. Reumatismo, 69(4), 175–183. https://doi.org/10.4081/reumatismo.2017.1007

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Similar Articles

<< < 1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.