TY - JOUR AU - Cozzi, F. AU - Zucchetta, P. AU - Durigon, N. AU - Marzola, M.C. AU - Bullo, A. AU - Favaro, M. AU - Bui, F. AU - Todesco, S. PY - 2003/06/30 Y2 - 2024/03/29 TI - Esophageal dysmotility in scleroderma patients with different disease forms and ANA patterns: a scintigraphic study in 100 cases JF - Reumatismo JA - Reumatismo VL - 55 IS - 2 SE - Articles DO - 10.4081/reumatismo.2003.86 UR - https://www.reumatismo.org/reuma/article/view/reumatismo.2003.86 SP - 86-92 AB - Objective: To define the prevalence and severity of esophageal involvement in systemic sclerosis (SSc) and its relationship with the different clinical forms and ANA specificities of the disease. Methods: A hundred consecutive patients with SSc, 48 with cutaneous limited, 26 with intermediate and 26 with diffuse form of disease, 49 with anti-centromere and 37 with anti-Scl70 ANA pattern, were submitted to scintigraphy using a semisolid orally ingested bolus to detect esophageal hypomotility. Results: An impairment of esophageal function has been observed in 68% of SSc patients. Esophageal dysmotility was significantly more frequent and severe in patients with cutaneous diffuse and intermediate forms of SSc and with anti- Scl70 ANA pattern. Conclusions: Esophageal involvement is very common in SSc. The scintigraphy confirms to be a useful and non invasive diagnostic method; moreover it permits to quantify the severity of the esophageal dysmotility by analyzing both global and segmental function. ER -