Nailfold capillaroscopic report: qualitative and quantitative methods

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Nailfold capillaroscopy (NVC) is a simple and non-invasive method used for the assessment of patients with Raynaud’s phenomenon (RP) and in the differential diagnosis of various connective tissue diseases. The scleroderma pattern abnormalities (giant capillaries, haemorrages and/or avascular areas) have a positive predictive value for the development of scleroderma spectrum disorders. Thus, an analytical approach to nailfold capillaroscopy can be useful in quantitatively and reproducibly recording various parameters. We developed a new method to assess patients with RP that is capable of predicting the 5-year transition from isolated RP to RP secondary to scleroderma spectrum disorders. This model is a weighted combination of different capillaroscopic parameters (giant capillaries, microhaemorrages, number of capillaries) that allows physicians to stratify RP patients easily using a relatively simple diagram to deduce prognosis.

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Lubatti, C., Ingegnoli, F., Gualtierotti, R., Boracchi, P., Zahalkova, L., Zeni, S., Soldi, A., & Fantini, F. (2008). Nailfold capillaroscopic report: qualitative and quantitative methods. Reumatismo, 60(4), 249–253. https://doi.org/10.4081/reumatismo.2008.249