https://doi.org/10.4081/reumatismo.2001.330

Helicobacter pylori eradication induce platelet recovery in idiopathic thrombocytopenic purpura

Vol. 53 No. 4 (2001)
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Authors

G. Emilia
office@pagepress.org
G. Longo
M. Luppi
G. Gandini
M. Morselli
L. Ferrara
S. Amarri
K. Cagossi
G. Torelli
Recent reports have suggested an association between Helicobacter pylori infection and idiopathic thrombocytopenic purpura (1TP). The prevalence of H pylori infection and the effect of its eradication in a series of 30 ITP patients were investigated. H pylori infection has been documented in 13 patients (43.33%) by 13C urea breath test and confirmed by histologic examination. Bacterium eradication with antibiotics, obtained in 12 of 13 infected patients (92.3%), led to a complete response in 4 (33.33%) and to a partial response (platelets 90 x IO^L-120 x IO’VL) in 2 (16.66%). The response was maintained for a median of 8.33 months, but 1 patient relapsed 7 months after eradication. Search for H pylori infection seems appropriate in ITP patients at diagnosis. Bacterium eradication provides a new good option for a non immunosuppressive treatment in some ITP patients. (Blood 2001; 97: 812-814)

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How to Cite

Emilia, G., Longo, G., Luppi, M., Gandini, G., Morselli, M., Ferrara, L., Amarri, S., Cagossi, K., & Torelli, G. (2001). Helicobacter pylori eradication induce platelet recovery in idiopathic thrombocytopenic purpura. Reumatismo, 53(4), 330. https://doi.org/10.4081/reumatismo.2001.330

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