Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease

Submitted: 27 July 2018
Accepted: 13 February 2019
Published: 24 October 2019
Abstract Views: 1272
PDF: 684
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Systemic sclerosis (SSc) is an uncommon connective tissue disorder characterized by multisystem involvement with fibrosis of skin and internal organs. Antibody formation is one of the hallmarks of SSc. Antinuclear antibodies (ANA) are positive in 97% of patients with SSc. We report a rare case where the patient was negative for ANA, Anti-topoisomerase I, Anti-centromere and Anti-RNA polymerase III antibodies.

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Saxena, D., Jain, D., Yadav, M., Giri, K., Yadav, T., & jain, P. (2019). Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease. Reumatismo, 71(3), 166–170. https://doi.org/10.4081/reumatismo.2019.1170