Case Reports
Vol. 71 No. 3 (2019)
Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: 27 July 2018
Accepted: 13 February 2019
Accepted: 13 February 2019
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Systemic sclerosis (SSc) is an uncommon connective tissue disorder characterized by multisystem involvement with fibrosis of skin and internal organs. Antibody formation is one of the hallmarks of SSc. Antinuclear antibodies (ANA) are positive in 97% of patients with SSc. We report a rare case where the patient was negative for ANA, Anti-topoisomerase I, Anti-centromere and Anti-RNA polymerase III antibodies.
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Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease. Reumatismo [Internet]. 2019 Oct. 24 [cited 2026 Jan. 5];71(3):166-70. Available from: https://www.reumatismo.org/reuma/article/view/1170
