Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease

  • D. Saxena Department of Medicine, Pt. B.D. Sharma University of Health Sciences, Rohtak, India.
  • D. Jain | jaindeepakdr@gmail.com Department of Medicine, Pt. B.D. Sharma University of Health Sciences, Rohtak, India.
  • M. Yadav Department of Medicine, Pt. B.D. Sharma University of Health Sciences, Rohtak, India.
  • K. Giri Department of Medicine, Pt. B.D. Sharma University of Health Sciences, Rohtak, India.
  • T. Yadav Department of Medicine, Pt. B.D. Sharma University of Health Sciences, Rohtak, India.
  • P. jain Department of Medicine, Pt. B.D. Sharma University of Health Sciences, Rohtak, India.

Abstract

Systemic sclerosis (SSc) is an uncommon connective tissue disorder characterized by multisystem involvement with fibrosis of skin and internal organs. Antibody formation is one of the hallmarks of SSc. Antinuclear antibodies (ANA) are positive in 97% of patients with SSc. We report a rare case where the patient was negative for ANA, Anti-topoisomerase I, Anti-centromere and Anti-RNA polymerase III antibodies.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2019-10-24
Info
Issue
Section
Case Reports
Keywords:
Systemic sclerosis, antinuclear antibodies, anti-topoisomerase I.
Statistics
  • Abstract views: 732

  • PDF: 378
How to Cite
Saxena, D., Jain, D., Yadav, M., Giri, K., Yadav, T., & jain, P. (2019). Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease. Reumatismo, 71(3), 166-170. https://doi.org/10.4081/reumatismo.2019.1170

Most read articles by the same author(s)